Sep 202012
 

กระเทียม สมุนไพรไทยจากหลักฐานทางประวัติศาสตร์พบว่า มีภาพวาดหัวกระเทียมปรากฏบนโลงศพมัมมี่อียิปต์ ประมาณ 3,200 ปีก่อนพระคริสต์ มีการขุดค้นพบกระเทียมฝังเป็นแนวรอบมหาราชวัง knosos  ในกรีซ และในปอมเปอี

 

 

 

 

นอกจากนี้ยังพบหลักฐานทางประวัติศาสตร์ว่าใช้กระเทียมเพื่อรักษา

  • · อาการปวดศีรษะ เจ็บคอ บำรุงร่างกายที่อ่อนแอ
    • · กระเทียมช่วยเพิ่มสมรรถภาพทางเพศ
    • · ตำราจีนและญี่ปุ่น ใช้กระเทียมช่วยลดความดัน
    • · ในสงครามโลกครั้งที่ 1 กระเทียมได้รับการยอมรับในการรักษาโรคไทฟัสและโรคบิด
    • · ในสงครามโลกครั้งที่ 2  แพทย์ชาวอังกฤษ รักษาแผลสด  เป็นยาฆ่าเชื้อ

นอกจากนี้ตามตำรายาไทยหลายเล่มยังได้ระบุสรรพคุณและประโยชน์ทางยาของกระเทียมได้หลายอย่าง

  • · ช่วยขับลม แก้ท้องอืดเฟ้อ บำรุงธาตุ
  • · ช่วยรักษาโรคกลากเกลื้อน
  • · ใช้น้ำคั้นหัวกระเทียมผสมน้ำอุ่นและเกลือ ใช้กลั้วคอเพื่อรักษาทอนซิลอักเสบ

กระเทียม allium sativum linn.

สารสำคัญ

ในหัวกระเทียมสดมีน้ำมันหอมระเหยอยู่ประมาณ 0.1-0.4 % มีสารสำคัญ ที่มีกำมะถันหลายชนิดเช่น alliin, allicin, diallyl disulfide, methyl n-propyl disulfide นอกจากนี้แล้วยังมีกรดกำมะถัน เช่น d-glutamyl-s-methylcysteine ส่วนกลิ่นของกระเทียมเกิดจาการย่อย allylcystein sulfoxide หรือ alliin ซึ่งไม่มีกลิ่นให้เป็นสาร allylthiosulfinote หรือ allicin ด้วยเอนไซม์  allinase

ฤทธิ์ทางเภสัชวิทยา

จากการทดลองในสัตว์ทดลองหลายชนิดพบว่ากระเทียมสามารถลดปริมาณของ cholesterol และ triglyceride ในเลือดได้

ส่วนการทดลองทางคลินิก พบว่า เมื่อให้น้ำมันหอมระเหยจากกระเทียม กับคนปกติและคนไข้โรคหัวใจที่มีระดับ Cholesterol สูง ในขนาดที่ได้ 0.25 mg /น้ำหนักตัว 1 กิโลกรัม เป็นเวลา 10 เดือน พบว่าระดับ Cholesterol ในเลือดลดลง และเมื่อใช้กระเทียมสดกับคนไข้ที่มีไขมันในเลือดสูง ในขาด 25 กรัม วันละ 3 เวลา เป็นเวลา 25 วัน พบว่า 1ใน 3 ของคนไข้ที่มีระดับ Cholesterol สูง ลดลงอย่างเห็นได้ชัด ส่วนอีก 2 ใน 3 ลดลงปกติ สารที่มีฤทธิ์ในการลด Cholesterol คือ allicin กระเทียมกับการลดความดันโลหิต

พบว่าสารสกัดด้วยแอลกอฮอล์ 95 % จากหัวกระเทียมสามารถลดความดันในคนไข้ที่มีความดันโลหิตสูงได้

กระเทียมกับการลดน้ำตาลในเลือด

จากผลการทดลองในสัตว์ทดลอง โดยการให้สารสกัดกระเทียมด้วย แอลกอฮอล์ให้กับกระต่ายที่ถูกทำให้เป็นเบาหวานด้วย alloxan โดยให้ในขนาด 0.25 กรัม ต่อน้ำหนักตัว 1 กิโลกรัม พบว่าสามารถลดน้ำตาลในเลือดได้ เมื่อเทียบกับยา tolbutamide ส่วนสาร allicin มีฤทธิ์ลดน้ำตาลในเลือดได้พอ ๆ กับ tolbutamide

กระเทียมยับยั้งเชื้อแบคทีเรียและเชื้อรา

น้ำคั้นกระเทียมและกระเทียมผงมีผลต่อการยับยั้งเชื้อแบคทีเรียที่เป็นสาเหตุของโรคหลายชนิด รวมทั้งเชื้อ klebsiella pneumoniae ซึ่งเป็นสาเหตุของโรคปอดบวม และเชื้อ mycobaerium tuberculosis อันเป็นสาเหตุของโรควัณโรค สารที่มีฤทธิ์ต้านเชื้อดังกล่าว คือ สารจำพวกซัลไฟด์ (sulfide) ซึ่งได้แก่ allicin, scordinin และ scordinin A

กระเทียมกับ HIV

จากการทดลองในหลอดทดลองพบว่าสารสกัดกระเทียมมีสาร ajoene ซึ่งไม่พบในกระเทียมสด แต่จะพบในกระเทียมที่หมักในน้ำมัน สาร ajoene สามารถป้องกัน CD4  Cell จากการติดเชื้อ HIV และยังช่วยลดการสร้างไวรัสตัวใหม่ในเซลล์ที่ติดเชื้อได้อีกด้วย

ใช้กระเทียมอย่างไร  ในชีวิตเราจะใช้กระเทียมในการประกอบอาหารหลายชนิด เช่น น้ำพริกกะปิ ผัดผัก ผักแกล้มหมูทอดกระเทียม ส้มตำ ฯลฯ แม้แต่เรากินข้าวขาหมูยังมีกระเทียมเป็นผักแกล้ม ถ้าจะอธิบายเป็นแบบสมัยใหม่น่าจะอธิบายได้ว่า เพราะข้าวขาหมูมีไขมันสูง ถ้าเรากินกับกระเทียม เข้าใจว่าจะช่วยลดไขมันที่เรากินไปได้ เราจะกินกระเทียมให้ได้คุณค่าของกระเทียมสูงควรจะใช้

“กระเทียมสด ดีที่สุด”

“กระเทียมไทย ให้ผลสูงสุด”

ใช้ขนาด 1 กรัมต่อน้ำหนักต่อหนึ่งกิโลกรัม (ประมาณ 10-15 กลีบต่อวัน)

นอกจากนี้กระเทียมยังช่วยรักษาโรคกลากเกลื้อนได้ โดยนำกระเทียมมาตำให้ละเอียดคั้นเอาน้ำทาบริเวณที่เป็นวันละ 2-3 ครั้ง 5-10 วัน อาการจะดีขึ้นและทาต่อจนกว่าจะหาย

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